Research Technician I – Dr. De Marco Lab
Title: Research Technician I – Dr. De Marco Lab
Location: Upper East Side
Org Unit: Center of Neurogenetics
Work Days: Monday-Friday
Exemption Status: Non-exempt
The De Marco lab at Weill Cornell Medicine in New York City has an opening for a research technician position. Under supervision, he/she will assist scientists with laboratory and investigative procedures related to our lab’s study of the developmental underpinnings of inhibitory neuronal diversity and cortical circuitry. Through the use of sophisticated genetic techniques, in combination with both functional (electrophysiology, optogenetics, in vivo calcium imaging) and anatomic (immunohistochemistry, viral tracing, neuronal morphological reconstruction) methods, our lab has uncovered essential roles for inhibitory neuronal activity in the developing cortex (Che et al., Neuron 2018; Duan et al Neuron 2020, Modol et al. Neuron 2020). Candidates with a strong background in Neuroscience and experience with mouse model systems are encouraged to apply. Find below a detailed description of the position.
Scientific & Investigative
· He/she will be responsible for animal husbandry, genotyping, surgeries, post-operative care, behavioral testing, in vivo 2P imaging, sectioning and histology.
· He/she will perform routine molecular biology laboratory procedures, such as PCR, protein and DNA electrophoresis, cloning and DNA preparation.
· He/she will perform data analyses using computer software and report results to the principal investigator(s).
· He/she will participate in planning and carrying out experiments and will assist in preparing research protocols.
· He/she will conduct library research and literature searches and will assist in editing scientific publications, abstracts and posters.
· He/she will help prepare and maintain detailed records, logs and summary reports of procedures and results including graphs, scientific calculations, and statistical analysis charting.
· May run routine biochemistry assays including western blotting and RT-PCR.
· May perform microscopic imaging analyses.
Administrative & Lab Management
· He/she will be responsible for the receipt, storage, cataloguing and shipment of samples within and between institutions.
· He/she will maintain laboratory equipment and facilities and manage inventory of supplies and/or reagents.
· He/she will ensure the safe laboratory practices are followed, including the use and disposal of chemicals and hazardous materials.
· He/she will provide technical support to faculty and staff in the training of new employees, residents, postdoctoral associates, fellows and students.
Bachelor’s Degree (preferably with an emphasis in Neurobiology/Neuroscience)
· Previous experience with mouse model system
· Bench lab related experience
· Minimum two-year commitment due to a substantial training effort associated with the position
Knowledge, Skills and Abilities
· Demonstrated organizational skills and ability to pay close attention to detail.
· Ability to plan and prioritize work while responding flexibly to rapidly changing priorities.
· Technicians may enrich their experience by taking advantage of the wealth of academic opportunities within and outside of the lab.
· He/she may work on self-directed projects.
· He/she has the potential to receive authorship on papers for which they have assisted with experiments.
· He/she has the potential to take graduate level courses at local institutions.
· He/she may find shadowing and/or volunteer opportunities in the hospital and in the community.
· He/she can attend some of the many lectures that occur throughout Weill Cornell, Sloan Kettering, and Rockefeller University.
Licenses and Certifications
Working Conditions/Physical Demands
· Standard laboratory conditions.
· Ability to work flexible hours.
· This position may handle radioactive material and/or biologic materials from human subjects as required.
· This position may require standing or sitting for long periods of time.
· This role may require working within Biological Safety Level 1, 2 and/or 3 facilities