Postdoctoral Fellow in Metabolism and Epigenetics | Van Andel Institute
A postdoctoral position is available in the laboratory of Dr. Adelheid Lempradl in the Department of Metabolism and Nutritional programing in the Van Andel Institute (VAI). Dr. Lempradl’s research focuses on the molecular mechanisms underlying intergenerational epigenetic inheritance. The lab is primarily interested in the effects of parental nutrition and toxin exposure on offspring health with the ultimate goal to find strategies to prevent transmission of adverse phenotypes to the next generation.
The postdoctoral researcher will explore the effects of maternal nutrition on early embryonic development. They will use a novel methodology developed in the lab to evaluate the metabolite and RNA content of single Drosophila oocytes and developing embryos. They will take advantage of the Drosophila genetic toolbox to manipulate members of metabolic pathways to gain a detailed understanding of the mechanisms underlying maternal dietary reprogramming.
The successful candidate will have the opportunity to be trained with both traditional and state-of-the-art technologies and will work in a highly interdisciplinary environment that allows close interaction with the growing research community at the Van Andel Institute (VAI). VAI is a leading independent non-profit biomedical life sciences research and education facility. The Institute is home to more than 200 scientists and support staff that work in on-site laboratories and in collaborative partnerships that span the globe. VAI has recently established a new research pillar in metabolic and nutritional programming. The department provides a stimulating multidisciplinary environment for state-of-the-art research to understand the intricate mechanics of cellular metabolism and their implications for human health. Its major focus is understanding how environmental exposures and metabolic dysfunction contribute to complex diseases such as diabetes, autoimmunity, cancer and neurodegeneration.
- A Ph.D. graduate with experience in the fields of metabolism, developmental biology and/or Drosophila research.
- Experience in some of the following skills: Drosophila work, metabolomics, transcriptomics, molecular biology techniques.
- Ability to coordinate and independently carry out a research project and present the outcome in a scientific presentation.
- Bioinformatics experience (e.g. analysis of NGS data) is a plus.
Description of a Successful Candidate:
- A collaborative, hands-on researcher who proactively shares knowledge and expertise with lab members and has an interest in providing mentorship to junior lab members.
- A self-motivated individual who is able to think critically to effectively design experiments and solve complex research problems.
- A strong ability to take initiative and work independently.
- Excellent written and oral communication skills.
This list will change as projects evolve and you should be open-minded to learn new things.
VAI provides postdoctoral training opportunities to scientists beginning their research careers (https://vari.vai.org/postdoctoral/). The fellowships are to help promising scientists advance their knowledge and research experience and at the same time support the research endeavors of VAI under the mentorship of a VAI Faculty member. All VAI Postdoctoral Fellows are encouraged to apply for external funding as soon as it is practical and reasonable after hire. Receiving a fellowship award provides recognition for both the fellow and VAI!
HOW TO APPLY
If you possess these attributes and enjoy working with motivated and committed people, we would welcome speaking with you and encourage you to apply today. https://bit.ly/3kHmPsW
We ask you to submit:
- A cover letter describing your research interests, experience, and how you might contribute to Lempradl Lab Research.
- An up-to-date Curriculum Vitae.
- A list of 2-3 individuals who have agreed to act as references along with their contact details.
Please contact Megan Doerr (Megan.Doerr@vai.org) for further information or questions, or if you have any difficulty with the application process.
VAI is actively striving to diversify its workforce and strongly encourages qualified individuals from underrepresented groups to apply. Van Andel Institute is an Equal Employment Opportunity (EEO) and Vietnam Era Veterans Readjustment Assistance Act (VEVRAA) Employer.
About Grand Rapids, MI
Van Andel Research Institute is located in downtown Grand Rapids, MI which is the second largest city in Michigan and the largest city in West Michigan. Grand Rapids offers a remarkable combination of cosmopolitan atmosphere and small-town warmth, known for its philanthropic and sustainability-driven community, and is ranked one of “America’s Top 100 Places to Live.” Located on the banks of the Grand River, Grand Rapids offers all the big-city excitement you would expect from a million-resident metropolis, featuring hundreds of restaurants and nightspots, theaters, museums, sports and concerts. The safe and clean downtown is surrounded by an eclectic mix of walk-able neighborhoods. With a medical and life sciences industry boom, strong entrepreneurial activity, dedication to green building and living, and innovative employers, Grand Rapids’ diverse economy continues to grow, offering endless career opportunities.