Aging and neurodegeneration using flies, worms and mice
The focus of the Kapahi Laboratory is to identify and characterize the mechanisms by which nutrients modulate aging and age-related diseases. This is being achieved by using an interdisciplinary approach combining genetic, pharmacological, biochemical and genomic approaches in invertebrate model systems C. elegans, D. melanogaster and mammalian cells. The broader significance of this research is to help uncover the role of nutrition in the etiology of age-related human diseases like diabetes, obesity and neurodegeneration.
The current Postdoctoral position involves investigating the mechanisms by which dietary restriction, glucose and Advanced Glycation Endproducts (AGEs) influence aging and age-related diseases using flies, worms or mice.
· Previous background in fly or mouse genetics is an advantage but not essential
· Willingness to write grants and manuscripts is necessary
The Buck Institute has an exceptional postdoctoral research program. We offer competitive salaries, excellent benefits, a dynamic and collaborative work environment, and new state-of-the-art facilities.