The National Biodefense Analysis and Countermeasures Center (NBACC) is a Department of Homeland Security (DHS) federal laboratory sponsored by the DHS Science and Technology Directorate and operated by the Battelle National Biodefense Institute, LLC (BNBI).
Works with a team of scientists in the National Biological Threat Characterization Center (NBTCC) at the NBACC to execute and analyze virology research that addresses specific scientific questions of national significance in support of biodefense preparedness, response and recovery. Areas of research include a range of topics related to the physical, biological and/or pathogenic properties of viral agents and aerosols containing viral agents. Work will be performed in state-of-the-art Biosafety Level BSL – 2, 3, & 4 and ABSL – 2, 3, & 4 facilities fully staffed and equipped with a wide range of technologies required for biodefense and infectious disease research.
MINIMUM REQUIRED QUALIFICATIONS
• Bachelor of Science and 2 years of current virology related experience or a Master’s degree including experience in at least two of the following methods: mammalian cell culture; virus, pseudo virus, viral vector, or virus-like particle propagation and titration; cell-based assays and laboratory automation; immunostaining of cells; PCR/qPCR/RT-qPCR/ddPCR; next generation sequencing; support of virology-related aerosol studies; support of virology-related animal protocols.
• Intermediate scientific proficiency in laboratory functions. Possesses the ability to identify issues with laboratory protocols, procedures, and experimental plans.
• Proficiency and clarity of oral and written communications are essential.
• Exemplary organizational skills with a proven track record of working effectively both independently and as a team player.
• Knowledge or experience with biocontainment facilities and procedures, laboratory safety, biosurety, and decontamination desirable.
• Skills and experience to support laboratory activities and work in accordance with NBACC’s management system (e.g., ISO).
• Must be a citizen of the United States, able to obtain and maintain an interim secret clearance leading to a top secret clearance, suitability for DHS, and a favorable adjudication of the Department of Justice (DoJ) for select agent access.
• Participation in the Immunization Program, Medical Surveillance Program and enrollment in the Personnel Reliability Program (PRP) is required.
• May be required to participate in NBACC’s alternative work and/or on-call schedule, dependent upon business needs.
• Provides technical and laboratory expertise to perform research projects in BSL-2, 3, & 4 laboratories aimed at addressing current virology threat characterization knowledge gaps, such as evaluation of viral growth, environmental decay, and virulence.
• Contributes in matrixed and cross-functional research teams that may include Aerobiology, Bacteriology, and Comparative Medicine (veterinary) staff.
• Adapts to potentially rapidly changing and high tempo project requirements to address national security issues with flexibility and resiliency.
• Maintains accurate and complete records and collects/analyzes technical and programmatic data as part of a project team in support of Project Lead or Principal Investigator. Performs quality control and peer review of data as assigned.
• Develops draft protocols, task-specific procedures and Standard Operating Procedures (SOPs). Identifies and documents inconsistency among SOPs or deviations from them, and promptly reports these to the Project Lead and/or management.
• Supports Principal Investigators during the writing of technical reports through review and summary of experimental records, initial processing and QC of raw data, and technical review of methods and data.
• Participates in the testing and evaluation of new technologies and protocols to improve the NBTCC’s ability to serve its customers.
• Applies prior hands-on experience and provides technical support for the application of viral genetic engineering methodologies, including use of genome editing technologies.
• Tasks will leverage proficiency in cell culture and in vitro viral assays (with experience in culturing a variety of viruses, preparation and quantitation of viral stocks using plaque assays or micro titration assays, viral immunoassays, viral neutralization assays, quantitative PCR, and molecular virology techniques including genome editing technologies).
• Possesses the ability to work on multiple science tasks simultaneously, while performing assignments outside of area of expertise.
• Exercises judgement within generally defined practices and policies in selecting methods and techniques for obtaining solutions.
• Follows established procedures on routine work, requires instruction only on new assignments, and is self-sufficient in monitoring and reporting on quality and compliance.
• Maintains a safe work environment by participating in specialized training and review of safety manuals and SOPs.
• Identifies departures from the Quality Management System (QMS) and initiates actions to investigate and prevent such occurrences.
• Develops techniques, prepares samples and performs test according to appropriate SOPs.
• Serves as a member of a team in developing, validating and maintaining methods for identifying and characterizing biological threat agents.
• With minimal supervision, operates, maintains, and characterizes the performance of equipment ensuring that reagents and supplies are maintained and used properly.
• Maintains appropriate records.
• Performs other assigned duties.
BNBI is an Affirmative Action/Equal Opportunity Employer. We celebrate diversity and are committed to creating an inclusive environment for all employees.