Benaroya Research Institute at Virginia Mason is committed to winning the fight against autoimmune diseases such as type 1 diabetes, rheumatoid arthritis, inflammatory bowel disease and multiple sclerosis, and immune system diseases such as allergies and asthma. BRI is an internationally recognized medical research institute that accelerates discovery by tackling questions from every angle, translating immunology breakthroughs into clinical therapies and healthier patients.
As a non-profit organization within the Virginia Mason Health System, BRI oversees all clinical research at Virginia Mason and BRI, uniquely combining the expertise of a world-renowned medical research institute with the remarkable care of a healthcare quality leader. BRI supports Virginia Mason clinical investigators in studies across a wide variety of diseases and conditions, such as cardiology and cancer, in addition to autoimmune diseases, allergy and asthma.
The Kwok Lab uses class II tetramer reagents and other state of art technologies, including single cell RNAseq experiments in examining antigen specific CD4+ T cells infectious diseases, peanut allergy, type 1 diabetes and rheumatoid arthritis.
- Lead experiments in characterization of autoreactive T cells in Rheumatoid Arthritis.
- Lead experiments in identification of T cell epitopes in Rheumatoid Arthritis.
- Carry out bench work experiments, including assay development, cell culture, flow cytometry assays and be responsible for checking and validating the results in each field of activity.
- Present results or summary of results to the project team or to other audiences as needed
- Write required documents such as experimental procedures, research articles and study reports.
- Provide oversight/ supervision of technicians or graduate students within the context of these studies.
- PhD Degree in Immunology/Biochemistry or similiar scientific discipline.
- Knowledge in cellular immunology with less than 3 years of postdoctoral experience.
- Specific specialization on human T and/or B cell immunology is required. Previous experience with MHC multimer staining, RNAseq, or knowledge in bioinformatics is a plus.
- Significant experience in multi-parameter flow cytometry, and in design/set up of cell based assays.
- Additional expertise in other laboratory techniques related to molecular biology and biochemistry research will also be considered.
- Excellent verbal and written communication skills with good organizational and analytical abilities.
All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, citizenship, disability or protected veteran status.